Biology NEET Full Syllabus Mock Test 180 Questions New Syllabus Mock Test - 11 PCB Single Correct MCQ
Published on: August 13, 2026

What is 'insertional inactivation' in recombinant DNA technology?

A
The insertion of DNA leading to increased gene expression
B
The insertion of foreign DNA disrupting a functional marker gene.
C
The insertion of DNA causing plasmid degradation
D
The insertion of DNA enhancing replication

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The correct answer is:
B

Insertional inactivation occurs when foreign DNA is inserted into a functional gene (e.g., tetracycline resistance gene or LacZ gene), disrupting its function. This helps in identifying recombinant colonies.

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